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Abdome

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Case report

Identification

35 year old female.

History of present ilness

Abdominal pain and discomfort of  1 month duration. The pain was mainly in the epigastrium and left hypochondrium. The pain was not radiating and was not associated with aggravating or relieving factors.

Past medical history

2016 and 2018 –  Cesarean section.

2022- Roux-en-Y gastric bypass surgery.

Physical exam

Upon abdominal examination, a large, palpable, mobile, non-tender mass was found in the left upper quadrant.

  • An etiological investigation was carried out.
  • The patient performed an abdominal CT scan.

 

Images

Abdominal CT scan

(A) Sagittal and (B) coronal non-contrast-enhanced abdominal CT scan images shows a circumscribed nodular lesion, heterogeneous, containing areas with higher density, located on the left hypochondrium, showing proximity to the enteroenteric anastomosis (yellow arrow).

Axial abdominal CT scan images with iodinated contrast administration in arterial phase (A) and portal venous phase (B) shows a circumscribed nodular lesion, heterogeneous, with discreet contrast enhancement on late portal phase,  located on the left hypochondrium, showing proximity with the renal parenchyma, spleen and adjacent intestinal loops, without signs of invasion.

 3D CT reconstruction

Three-dimensional CT reconstruction of the structures of the abdomen shows a circumscribed nodular lesion (red),  located on the left hypochondrium, showing proximity to the left lobe of the liver (orange),  left kidney (yellow), spleen (green), without signs of invasion.

 

  • Considering the characteristics of the nodular lesion, an abdominal MRI with gadolinium contrast was performed.

 

Abdominal MRI

Abdominal MRI Axial images.

(A) T2-weighted shows the presence of circumscribed and heterogeneous mass located on the left hypochondrium with T2-hypointense central component surrounded by T2-hyperintense signal.

(B) Nonenhanced T1-weighted shows predominance of isointense signal of the mass.

Abdominal MRI axial images, (A) post contrast-enhanced T1-weighted and (B) delayed phase contrast-enhanced T1-weighted, shows the presence of circumscribed and heterogeneous mass with heterogeneous increased enhancement on delayed phase of gadolinium contrast, located on the left hypochondrium, showing contact with the renal parenchyma, pancreatic tail and adjacent intestinal loops, without signs of invasion.

Abdominal MRI Coronal images. (A) fat-suppressed T2-weighted and (B) T2-weighted.

The presentation shows a large circumscribed and heterogeneous mass with T2-hypointense central component surrounded by T2-hyperintense signal, located on the left hypochondrium, showing contact with the intestinal loops.

Desmoid tumor at the enteroenteric anastomosis after a Roux-en-Y gastric bypass surgery

Leonardo Manrique e Silva – Second-year Radiology Resident Ultrax – Instituto de Radiodiagnóstico de Rio Preto | Advisor: Dra. Maria Laura Silveira de Castro
  • Age group ( 20 – 40 years )
  • They are seen more in women (2:1)
  • Previous surgery is a risk factor
Imaging Features at CT
  • Appears as a soft-tissue mass, either sharply marginated, or with ill-defined infiltrative margins.
  • Shows variable attenuation, with hyper and hypoattenuation, probably reflecting collagen and myxoid elements.
  • Enhancement is variable, with the majority of the masses demonstrating mild-to-moderate enhancement.
Imaging Features at MR Imaging
  • On T1-weighted images, desmoids are hypo or isointense to skeletal muscle.
  • T2-weighted images are iso- to hyperintense to skeletal muscle.
  • Enhancement with gadolinium contrast, shows moderate enhancement with hypo-intense bands because of collagen bundles.
DIFFERENTIAL DIAGNOSIS Small bowel neuroendocrine tumor – X
  • Polypoid or plaque-like appearance.
  • Hyper-enhancing on arterial phase at CT scan.
  • Can cause distortion and focal fixation of the affected small bowel loop.
  • Calcifications are present in up to 70% of cases.
Solitary fibrous tumor – X
  • More common in the 5th to 7th decades.
  • Usually have relatively homogeneous low-to-intermediate T1 and T2 signal intensity relative to skeletal muscle.
  • May be areas of subacute hemorrhage that have high T1 signal intensity.
  A laparotomy with midline incision was performed due to the large size of the mass. A surgical resection of the mass and anatomopathological study with immunohistochemistry were performed. Laparotomy image shows a mass (blue arrow) adhered to the enteroenteric anastomosis (green arrow). Macroscopic analysis shows a mass (blue arrow) adhered to the enteroenteric anastomosis (green arrow). Photomicrograph of core biopsy specimen shows a moderately cellular neoplasm composed of long fascicles of uniform spindle cells (blue arrow)  adhered to the small bowel (green arrow). (Hematoxylin-eosin stain; original magnification) Photomicrograph of immunohistochemistry of the tumor cells showed positive nuclear staining for beta-catenin but negative staining for DOG-1, CD34, S-100, SMA and desmin consistent with the diagnosis of desmoid tumor.   PATIENT OUTCOME
  • The patient’s postoperative course was uneventful, and she was discharged on the fifth day post-operation.
  • She showed no complication or recurrence during her follow-up.
REFERENCES
  1. Van Houdt WJ, et al. Outcome of primary desmoid tumors at all anatomic locations initially managed with active surveillance. Ann Surg Oncol. 2019;26(13):4699–706.
  2. Kasper B. Desmoid tumor: A focus set on a challenging but understudied rare disease. Cancer. 2019 Apr 12.
  3. De Bree E, et al. Desmoid tumors: need for an individualized approach. Expert Rev Anticancer Ther. 2009;9(4):525–35.
  4. Crago AM, Denton BT, Salas S, Dufresne A, Mezhir JJ, Hameed M, et al. A Prognostic Nomogram for Prediction of Recurrence in Desmoid Fibromatosis. Annals of Surgery. 2013 Aug 1;258(2):347–53.
  5. Braschi-Amirfarzan M, Keraliya AR, Krajewski KM, Tirumani SH, Shinagare AB, Hornick JL, et al. Role of Imaging in Management of Desmoid-type Fibromatosis: A Primer for Radiologists. RadioGraphics. 2016 May;36(3):767–82.
  6. Medas R, Coelho R, Bessa-Melo R, Pereira P, Macedo G. Desmoid Tumor after Sleeve Gastrectomy: Case Report and Literature Review. Portuguese journal of gastroenterology. 2023 Sep 27;1–5.